Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of leishmania mexicana

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  • who: Julie Kov#_#x00E1 et al. from the Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Glasgow have published the paper: Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana, in the Journal: (JOURNAL) of March/19,/2018
  • what: The authors present a study of a L mexicana TKT knock-out (Δtkt) cell line. The authors show here that TKT is essential for L mexicana virulence in mice, despite being dispensable in cultured promastigotes. The authors show that TKT is involved . . .

     

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