Deletion of ucp2 in inos deficient mice reduces the severity of the disease during experimental autoimmune encephalomyelitis

HIGHLIGHTS

• who: Autoimmune Encephalomyelitis and colleagues from the de Biochimie A, France, Department of Dermatology, University of Luebeck, Luebeck, Germany, Department of have published the article: Deletion of UCP2 in iNOS Deficient Mice Reduces the Severity of the Disease during Experimental Autoimmune Encephalomyelitis, in the Journal: (JOURNAL) of April/11,/2011
• what: Considering the above results and data available in literature, the authors propose the following scenario (Fig 6). Interestingly, the study shows that inactivation of both Ucp2 and iNos genes leads to a less severe disease.

SUMMARY

Pathology of EAE is . . .

 



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