Deletion of

HIGHLIGHTS

• who: Kristen R. Ibanez from the Center for Translational Research in Neurodegenerative Disease, University of Florida, Center Drive, Gainesville, FL, USA have published the research: Deletion of, in the Journal: (JOURNAL)
• what: Using multiple transcriptomic datasets the authors show that expression of Abi3 and Gngt2 are tightly correlated in rodent models of AD and human brains suggesting a tight co-expression relationship. Using in vitro culture assays the authors show that the AD-associated S209F mutation alters the extent of ABI3 phosphorylation. To survey how amyloid plaques and gliosis in this model affect neuronal health . . .
  

   

  

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