HIGHLIGHTS
- What: The authors investigated novel bone regenerative therapies downstream of JAGGED1 (JAG1). This study provides convincing evidence for an innovative regenerative treatment for pediatric craniofacial bone loss using Jagged1PEG-MAL hydrogel with pediatric human bone cells.
- Who: Genetics and collaborators from the Department of Pediatric Otolaryngology, Emory, Parker HPetit Institute for have published the article: Delivery of A Jagged1-PEG-MAL hydrogel with Pediatric Human Bone Cells Regenerates Critically- Sized Craniofacial Bone Defects, in the Journal: eLife assessment
- How: The authors hypothesized that delivery of JAG1 and induction of its downstream NOTCH non . . .
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