Delivery of engineered extracellular vesicles with mir-29b editing system for muscle atrophy therapy

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  • who: Rui Chen from the Eight-week-old male C BL/ J mice were purchased from Charles River (Beijing, China) and maintained in the SPF laboratory animal facility of Shanghai University (Shanghai, China)All procedures with animals were performed in accordance with the guidelines on the use and care of laboratory animals for biomedical research published by the National Institutes of Health (No. , , revised, ), and the experimental protocol was reviewed and approved by the ethical committee of Shanghai University. A detailed method of the mouse muscle atrophy models has been previously described in our work [4]. Briefly . . .

     

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