Delivery of the selenoprotein thioredoxin reductase 1 to mammalian cells

HIGHLIGHTS

  • who: October et al. from the Institute of Biotechnology (ASCR), Yale University, United States have published the article: Delivery of the selenoprotein thioredoxin reductase 1 to mammalian cells, in the Journal: (JOURNAL)
  • what: From there, TrxR1 transfers electrons to the C-terminal selenylsulfide active frontiersin.org 10.3389/fmolb.2022.1031756 over-expressing TrxR1, yet no experiments were provided to demonstrate incorporation of Sec in TrxR1 or to evaluate apoptosis (Lu et_al, 2022). The work demonstrated a novel approach to deliver an active and full-length human selenoprotein to mammalian cells via fusion with a . . .

     

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