Depdc1b promotes development of cholangiocarcinoma through enhancing the stability of cdk1 and regulating malignant phenotypes

HIGHLIGHTS

  • who: Zhenhai Zhang from the Chiba Cancer Center, Japan Kanazawa University, Japan have published the paper: DEPDC1B promotes development of cholangiocarcinoma through enhancing the stability of CDK1 and regulating malignant phenotypes, in the Journal: (JOURNAL)
  • what: The authors aimed to explore the role of DEPDC1B in CCA. The outcomes of this study provided a novel insight into the biological functions of DEPDC1B in the development and progression of CCA and preliminarily explored the underlying mechanism. In this study, based on mechanistic research, CDK1 was proposed as the downstream target of DEPDC1B in the regulation of . . .

     

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