Depletion of gim5 causes cellular fragility, a decreased glycosome number, and reduced levels of ether-linked phospholipids in trypanosomes*

HIGHLIGHTS

• who: Frank Voncken from the (UNIVERSITY) have published the article: Depletion of GIM5 Causes Cellular Fragility, a Decreased Glycosome Number, and Reduced Levels of Ether-linked Phospholipids in Trypanosomes*, in the Journal: (JOURNAL) of February/20,/2003
• what: The authors show here that procyclic trypanosomes, adapted for life in the Tsetse fly vector, survive without GIM5A and with very low levels of GIM5B.
• how: The results indicated that bloodstream trypanosomes required both PEX11 and the PEX11-related protein GIM5B for survival. In this experiment wild-type trypanosomes (strain 449) were used for transfection . . .
  

   

  

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