Depletion of ripk1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis

HIGHLIGHTS

  • who: Muhammad Farooq from the (UNIVERSITY) have published the research: Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis, in the Journal: (JOURNAL)
  • what: This study aimed to define the role of RIPK1 in hepatocytes during fulminant viral hepatitis a worldwide syndrome mainly observed in hepatitis B virus (HBV) infected patients. The investigations demonstrated that RIPK1 protects hepatocytes from TNF-α secreted from macrophages during viral induced fulminant hepatitis.
  • how: The study was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory . . .

     

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