Derivatives of 2-aminobenzimidazole potentiate asic open state with slow kinetics of activation and desensitization

HIGHLIGHTS

  • who: January and collaborators from the Meritorious Autonomous University of Puebla, Mexico have published the article: Derivatives of 2-aminobenzimidazole potentiate ASIC open state with slow kinetics of activation and desensitization, in the Journal: (JOURNAL)
  • what: The authors focused on finding new ASIC modulators, bearing in mind that they can be selective ASIC2a modulators. The experiments described above were performed with a coapplication protocol, in which the drugs were applied simultaneously with acidifications.
  • how: The experiments were conducted in accordance with the Rules of the Committee for the Care and Use of Animals . . .

     

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