HIGHLIGHTS
- who: Luke O. Ouma from the Oncology Institute of Southern Switzerland (IOSI), Switzerland Meiji Pharmaceutical University, Japan have published the research: Design and analysis of umbrella trials: Where do we stand?, in the Journal: (JOURNAL)
- what: The authors conduct a comprehensive review with a focus on (i) the design and analysis of recent umbrella trials, and_(ii) proposed trial designs and statistical methods available for umbrella trials. Thirty-eight umbrella trials, all investigating experimental drugs, were identified in the review ; a summary of their key characteristics is presented in Tables 1, 2. Hypotheses not straightforward . . .
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