Design and development of a self-assembling protein nanoparticle displaying pfhap2 antigenic determinants recognized by natural acquired antibodies

HIGHLIGHTS

• who: Farhad Zahedi and collaborators from the Iran, Chemical and Petroleum Engineering Department (BBRC), Sharif University of Technology, Tehran have published the research work: Design and development of a self-assembling protein nanoparticle displaying PfHAP2 antigenic determinants recognized by natural acquired antibodies, in the Journal: PLOS ONE of May/12,/2022
• what: The authors designed a nanovaccine candidate molecule for malaria using the SAPN platform and evaluated it in silico and in_vitro.
• how: For this experiment recombinant PfGCS1 antigen (aa 176-195 (cd loop) fused to aa 311-609 of PfGCS1 antigen containing . . .
  

   

  

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