Design, development, and optimisation of smart linker chemistry for targeted colonic delivery—in vitro evaluation

HIGHLIGHTS

  • who: Heba S. Abd-Ellah and collaborators from the Department of Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Parkville, VI, Australia Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt have published the paper: Design, Development, and Optimisation of Smart Linker Chemistry for Targeted Colonic Deliveryu2014In Vitro Evaluation, in the Journal: Pharmaceutics 2023, 15, 303. of 12/01/2023
  • what: The aim of this study was to explore the potential of aminoalkoxycarbonyloxymethyl (amino-AOCOM) ether prodrugs as a general approach for future colonic delivery. This study provides initial proof of concept regarding the . . .

     

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