Design, synthesis and activity study of pyridine derivatives as highly effective and selective tyk2 inhibitors

HIGHLIGHTS

• who: Chaoying Cheng et al. from the Frontiers Center for Materiobiology and Dynamic Chemistry, East China University of Science and Technology, Meilong Road have published the article: Design, Synthesis and Activity Study of Pyridine Derivatives as Highly Effective and Selective TYK2 Inhibitors, in the Journal: BioMed Research International of 28/03/2022
• what: Through the research of BMS, it is found that the activity of TYK2 kinase can be regulated by inhibiting the activity of the JH2 region of TYK2, so as to achieve the purpose of selective inhibition.

SUMMARY

The . . .

 



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