Design, synthesis and antimicrobial evaluation of new n-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)(hetero)aryl-2-carboxamides as potential inhibitors of mycobacterial leucyl-trna synthetase

HIGHLIGHTS

  • who: Petr u0160lechta et al. from the Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in, Charles University, have published the research work: Design, Synthesis and Antimicrobial Evaluation of New N-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)(hetero)aryl-2-carboxamides as Potential Inhibitors of Mycobacterial Leucyl-tRNA Synthetase, in the Journal: (JOURNAL)
  • what: Within this work, nineteen derivatives of N-(1-hydroxy-1,3-dihydrobenzo[c][1,2] oxaborol-6-yl)(hetero)aryl-2-carboxamides have been prepared and fully characterized.
  • how: All the experiments . . .

     

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