Design, synthesis, and antiproliferative activity of new 5-chloro-indole-2-carboxylate and pyrrolo[3,4-b]indol-3-one derivatives as potent inhibitors of egfrt790m/brafv600e pathways

HIGHLIGHTS

• who: Lamya H. Al-Wahaibi et al. from the Department of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia have published the Article: Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways, in the Journal: Molecules 2023, 1269 of 23/01/2023
• what: The findings of the study show that the tested compounds have potent antiproliferative activity and are effective at inhibiting both EGFR and BRAFV600E.
• how: After four days . . .
  

   

  

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