Design, synthesis, and antitumor evaluation of novel mono-carbonyl curcumin analogs in hepatocellular carcinoma cell

HIGHLIGHTS

  • who: Pan Yu and collaborators from the College of Medicine, Anhui University of Science and Technology, Huainan, China have published the article: Design, Synthesis, and Antitumor Evaluation of Novel Mono-Carbonyl Curcumin Analogs in Hepatocellular Carcinoma Cell, in the Journal: Pharmaceuticals 2022, 950 of 22/06/2022
  • what: The authors attempt to design new curcumin analogs modified on the u03b2-diketone structure and hydroxy on benzene to increase the anti-human hepatocellular carcinoma (HCC) activity. As shown in Figure 1A, curcumin analogs in group B and group C showed stronger anti-proliferation activities than groups . . .

     

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