HIGHLIGHTS
- What: The authors design and synthesize a novel series of 2-styrylquinoline derivatives with substitution on C-6 of quinoline ring with Br, H, NO2 and C-4′ of styryl moiety with electronwithdrawing groups from isatin and ketones using Pfitzinger reaction and evaluation of their antimicrobial and anticancer properties. The studies were repeated three 2954 Saini et_al times in separate trials and the mean MIC values were used to report the results. In the current study, the novel 2-styrylquinolines derivatives were designed, synthesized and biologically evaluated as potential antimicrobial agents with additional anticancer activities.
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