HIGHLIGHTS
- who: September and colleagues from the Cairo, United States have published the article: Design, synthesis and biological evaluation of 9-aryl-5 -pyrido [4,3- ]indole derivatives as potential tubulin polymerization inhibitors, in the Journal: (JOURNAL)
- what: 4 Experimental section
- how: Among the compounds the authors designed 7k exhibited the most potent anticancer activity against HeLa cells which was weaker cytotoxic than CA-4. The results indicated that analogue 7k caused cell arrest at G2/M phase which was a representative characteristic of tubulin polymerization inhibitors. The image results were presented by confocal . . .
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