HIGHLIGHTS
- who: Adrien Chastel from the Department of Nuclear Medicine, University Hospital of Bordeaux, Bordeaux, France have published the Article: Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides, in the Journal: (JOURNAL)
- what: The authors describe the design of a multifunctional radiolabeled neuropeptide-Y (NPY) conjugate to address radiolanthanides to the nucleus of cells naturally overexpressing the human Y1 receptor (hY1R). Unfortunately, fast degradation of conjugate In-pb12 was observed, with ~20% of the initial radiopeptide left intact 1 h after incubation at 37 °C. SPECT/CT . . .
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