Design, synthesis and biological evaluation of arylpyridin-2-yl guanidine derivatives and cyclic mimetics as novel msk1 inhibitors. an application in an asthma model

HIGHLIGHTS

• who: Maud Bollenbach and colleagues from the Laboratoire d'Innovation Thérapeutique, Institut du Médicament (IMS), UMR, CNRS have published the article: Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model, in the Journal: Molecules 2021, 391 of /2021/
• what: Considering ing this, the authors focused the attention on the use of diprotected-6-chloropyridine guanidine this, focused the attention the use of diprotected-6-chloropyridine guanidine 3 as 3 as the authors a key precursor for rapidon introduction . . .
  

   

  

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