Design, synthesis and biological evaluation of ligustrazine-flavonoid derivatives as potential anti-tumor agents

HIGHLIGHTS

  • who: Hui Wang et al. from the School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China have published the Article: Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents, in the Journal: (JOURNAL)
  • what: In this study, although chalcone was not selected, compounds 14 and 16 with chalcone as the mother nucleus were obtained via synthesis.
  • how: All the synthesized compounds were tested for their cytotoxicities on five tumor cell lines (HepG-2 Bel-7402 HT-29 MCF-7 and HeLa) using the standard MTT assay . . .

     

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