Design, synthesis, and in vitro activity of pyrazine compounds

HIGHLIGHTS

  • who: Panagiotis Parsonidis and collaborators from the RGCC International GmbH, Baarerstrasse, Zug, Switzerland have published the research: Design, Synthesis, and In Vitro Activity of Pyrazine Compounds, in the Journal: Molecules 2019, 24, x Molecules 2019, 24, x of /2019/
  • what: The authors started with prolines as cyclic amines confirming that the structures had the same interactions with those already existing in the literature and here the authors report one new hydrogen bond. The authors designed three small_molecules using structureinhibitor SHP099-SHP2 complex. The aim of the study was to determine the utility of substituted pyrazine . . .

     

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