Design, synthesis and mechanistic studies of novel isatin-pyrazole hydrazone conjugates as selective and potent bacterial metap inhibitors

HIGHLIGHTS

• who: Iram Irfan and colleagues from the Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, India University, New Delhi, India have published the Article: Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors, in the Journal: Antibiotics 2022, 1126 of /2022/
• what: The aim of this experiment was to assess the in_vivo toxicity of PS9 using larvae of G. mellonella. The biochemical and various cellbased assays performed in this study demonstrate that PS9 compound has the potential to be developed as an effective and . . .
  

   

  

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