Design, synthesis, in vitro, and in silico insights of 5-(substituted benzylidene)-2-phenylthiazol-4(5h)-one derivatives: a novel class of anti-melanogenic compounds

HIGHLIGHTS

• who: Dahye Yoon et al. from the Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University have published the paper: Design, Synthesis, In Vitro, and In Silico Insights of 5-(Substituted benzylidene)-2-phenylthiazol-4(5H)-one Derivatives: A Novel Class of Anti-Melanogenic Compounds, in the Journal: Molecules 2023, 3293 of 21/Nov/2022
• what: Novel anti-melanogenic compound (Z)-5-benzylidene-2-phenylthiazol-4(5H)-one ((Z)BPT) derivatives were designed and synthesized from thiobenzamide and bromoacetic acid.
• how: The docking simulation results are shown in Figure 5. as a . . .
  

   

  

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