Designed β-boomerang antiendotoxic and antimicrobial peptides

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• who: Anirban Bhunia from the Anirban Bhunia, Harini Mohanram, Prerna NDomadia, Jaume Torres, and Surajit Bhattacharjya, From the School of Biological Sciences, Division of Structural and Computational Biology, Nanyang Technological University, Singapore , Lipopolysaccharide (LPS), an integral part of the outer membrane of Gram-negative bacteria, is involved in a variety of biological processes including inflammation, septic shock, and resistance to host-defense molecules. LPS also provides an environment for folding of outer membrane proteins. In this work, we describe the structure-activity correlation of a series of, residue peptides in LPS. NMR structures of the peptides derived . . .
  

   

  

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