Designed multifunctional peptides for intracellular targets

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• who: Davor Juretiu0107 from the predictions are, however, questionable because all cell types can be penetrated, and the selectivity for cancer cells is not expected without some tumor-homing mechanismThere are tumor-homing peptides that can be fused to the MTD. Seo et_al [178] used CGNKRTRGC and CNGRCVSGCAGRC tumor vascular-targeting motifs discovered by Arap et_al [231] to design selective MTD-CPP hybrids. The C Pred server by Tang et_al [23] predicts that the hybrid peptide CGNKRTRGCGGKLLNLISKLF (named TU3: MTD) gains the CPP ability. That was verified in experiments by Seo et_al [178]. The Chosun University from . . .
  

   

  

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