Destin2: integrative and cross-modality analysis of single-cell chromatin accessibility data

HIGHLIGHTS

• who: Methods et al. from the Duke University, United States have published the paper: Destin2: Integrative and cross-modality analysis of single-cell chromatin accessibility data, in the Journal: (JOURNAL)
• what: The authors propose Destin2, a successor to the previous unimodal method Destin (Urrutia et_al, 2019), for Frontiers in Genetics In using these multiomic datasets, the authors demonstrate how Destin2`s cross-modality analyses preserve true cell-cell similarities by using the matched cell information as ground truth. As an example, the authors show the reconstruction of the true branching lineages during human hematopoietic differentiation . . .
  

   

  

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