HIGHLIGHTS
- who: Athena Chen from the (UNIVERSITY) have published the research work: Detecting antibody reactivities in Phage ImmunoPrecipitation Sequencing data, in the Journal: (JOURNAL) of 31/08/2022
- what: The output from PhIP-Seq experiments are read count matrices, similar to RNA-Seq data, but important differences in the data structures, experimental design, and study objectives exist between the two sequencingbased methods. Using simulation studies and data sets from existing HIV and SARS-CoV-2 studies, the authors investigate what improvements in sensitivity and specificity can be made, highlight the importance of empirical Bayes methods, and . . .
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