HIGHLIGHTS
- who: Tu00fcns AI et al. from the Laboratory of Molecular Oncology, West German Cancer Center, Department of Medical Oncology, University Hospital Essen, Computer Science, Saarland University, Saarbru00fccken, Germany have published the paper: Detection and Validation of Circular DNA Fragments Using Nanopore Sequencing, in the Journal: (JOURNAL)
- how: This paper introduces a read mapping based approach to detect ecDNA in tumor cells. The authors implemented a Snakemake (Mu00f6lder et_al 2021) workflow for detecting circular DNA fragments from nanopore sequencing data using the protocol outlined in Section 2.1 see Figure 3. While the authors designed the . . .
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