Detection of hiv cdna point mutations with rolling-circle amplification arrays

HIGHLIGHTS

  • who: Lingwei Wu from the State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China have published the research: Detection of HIV cDNA Point Mutations with Rolling-Circle Amplification Arrays, in the Journal: Molecules 2010, 15, 619-626 of 28/Dec/2009
  • what: This approach shows greater sensitivity than conventional PCR .
  • how: RCA amplification products A and B were hybridized with fluorescent probes (FPs) and solid sequence probes respectively and the scan results were showed on Figure 3.

SUMMARY

    On a target DNA, the two ends of the probe become . . .

     

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