HIGHLIGHTS
SUMMARY
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer that frequently metastasizes to drain lymph nodes and distant organs; therefore, a prompt diagnosis is required. The late region encodes for the capsid proteins, viral protein 1 (VP1) and viral protein 2 (VP2) and for two mature microRNAs (miRNAs), MCV-miR-M1-5p and MCV-miR-M1-3p, which are thought to modulate viral_replication. Interposed between these two regions resides the Non-Coding Control Region (NCCR), which contains the origin of replication (Ori) and the promoters and enhancers for the regulation of early . . .
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