Detection of somatic copy number deletion of the cdkn2a gene by quantitative multiplex pcr for clinical practice

HIGHLIGHTS

• who: Yuan Tian from the City University of Hong Kong, Hong Kong SAR, China have published the research work: Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice, in the Journal: (JOURNAL)
• what: The authors characterized patterns of estimated genomic coordinates for SCNDs in a set of tumor suppressor genes using the public Catalogue Of Somatic Mutations The authors report that there are CDRs in many tumor suppressor genes, such as CDKN2A, miR31HG, PTEN, and RB1, which are commonly inactivated by SCND in various human cancers .
 



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