Detection of vascular notch3 deposits in unfixed frozen skin biopsy sample in cadasil

HIGHLIGHTS

  • who: Akihiko Ueda from the Department of Neurology, Kumamoto University, Kumamoto, Japan, Department of Molecular Laboratory Medicine have published the research work: Detection of Vascular Notch3 Deposits in Unfixed Frozen Skin Biopsy Sample in CADASIL, in the Journal: (JOURNAL)
  • what: In this study, 10 of 43 cases were identified as positive of staining of Notch3 and/or GOM.
  • how: Immunohistochemical Staining of Vascular Notch3 ECD Deposits For immunohistochemical staining of vascular Notch3 ECD deposits the authors used 10-u00b5m unfixed frozen skin sections.

SUMMARY

    In contrast, unfixed frozen tissue . . .

     

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