Determination of phage load and administration time in simulated occurrences of antibacterial treatments

HIGHLIGHTS

SUMMARY

    In vivo, the situation is even more complicated because it is necessary to account for the immune_response against both bacteria and phages. The terms H(t) and h(t) represent the immune_response against bacteria and phages, respectively. The increasing application of phages for eco-restoration, food safety, and sterilization of surfaces implies that phage-derived antibacterial treatments need to work even in the absence of a complementary immune_response. Within the present framework, as in Payne et_al`s study, the effectiveness of the therapy was based on the complete removal of the target bacterium and . . .

     

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