Determination of pharmacokinetics and tissue distribution of a novel lutetium-labeled psma-targeted ligand, 177lu-dota-psma-gul, in rats by using lc-ms/ms

HIGHLIGHTS

  • who: Chang Ho Song from the SchoolSungkyunkwan University have published the paper: Determination of pharmacokinetics and tissue distribution of a novel lutetium-labeled PSMA-targeted ligand, 177Lu-DOTA-PSMA-GUL, in rats by using LC-MS/MS, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    Briefly, 175Lu-DOTA-PSMA-GUL was synthesized by mixing DOTA-PSMA-GUL solution and 175LuCl3 solution. Tissue distribution of 175Lu-DOTAPSMA-GUL was assessed at steady_state following i.v. infusion at two dose levels that aimed to obtain ­Css,target of 3,000 ng/mL and 6,000 . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?