HIGHLIGHTS
- who: Kyung Youn Lee and colleagues from the University of Veterinary Medicine Vienna, Austria have published the article: Development and characterization of a CRISPR/Cas9-mediated RAG1 knockout chicken model lacking mature B and T cells, in the Journal: (JOURNAL)
- what: This model has potential to aid elucidation of gd T_cell function, to identify interaction between innate immunity and adaptive immunity, and to contribute to vaccinology research.
- how: To characterize the targeted genome integration the authors conducted sequencing analysis of the 5' and 3' junction regions containing the endogenous RAG1 gene and donor . . .
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