Development and characterization of a panel of anti-idiotype antibodies to 1c10 that cross-neutralize hiv-1 subtype b viruses

HIGHLIGHTS

  • who: Yu Kaku from the Kansai Medical, Japan have published the research: Development and characterization of a panel of anti-idiotype antibodies to 1C10 that cross-neutralize HIV-1 subtype B viruses, in the Journal: (JOURNAL)
  • what: In the IGHV3 BCR, the authors focused on five Asp residues and one Asn residue at the same positions as the predicted contact residues of 1C10 shown in Figure 3A. The aim of this study was using anti-Id abs to investigate the structural features of 1C10 as a potent ladle-type anti-V3 nAb without a long . . .

     

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