Development and characterization of an amorphous solid dispersion of furosemide in the form of a sublingual bioadhesive film to enhance bioavailability

HIGHLIGHTS

  • who: Viviana De Caro and colleagues from the Consiglio Nazionale delle Ricerche, Istituto Biofisica-UOP Palermo, Palermo, PA, Italy have published the paper: Development and Characterization of an Amorphous Solid Dispersion of Furosemide in the Form of a Sublingual Bioadhesive Film to Enhance Bioavailability, in the Journal: (JOURNAL)
  • what: As a consequence, the aim of this work is the design of an adequate new formulation capable of improving the pharmacokinetics of FUR when administered sublingually. The experiments were started by placing 0.2 mL of simulated saliva (pH 6.8, 37 ◦ C) on the disk . . .

     

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