Development and characterization of an hcmv multi-antigen therapeutic vaccine for glioblastoma using the unite platform

HIGHLIGHTS

  • who: Amit S. Adhikari from the Immunomic Therapeutics, Rockville, MD, United States University of Pittsburgh, United States have published the article: Development and Characterization of an HCMV Multi-Antigen Therapeutic Vaccine for Glioblastoma Using the UNITE Platform, in the Journal: (JOURNAL)
  • what: In the present study, using ITI-1001 vaccination of naive mice, the authors demonstrated strong antigen-specific humoral response and T-cell activation in both CD8 and CD4 T-cell compartments as evaluated by their ability to secrete high levels of IFNg and TNFa. This model has a low mutational burden and is . . .

     

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