HIGHLIGHTS
- What: This study demonstrated how rapidly pretreatment drug resistance is spreading in these countries, particularly in sub-Saharan Africa. The largest cluster in the study , cluster 0, indicates that protease, or PI, is consistently the main focus of academic circles. Since commonly utilized MD simulations favorably influence the resistance mechanism, the authors propose that a mechanism-related research force use this technique. Following this study, further drug-related tests were carried out to obtain additional information or to determine the mutation mechanism involved.
- Who: Xuannan Chen and collaborators from the University of Texas Southwestern Medical . . .
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