Development and evaluation of a physiologically based pharmacokinetic model for predicting haloperidol exposure in healthy and disease populations

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  • who: Mohammed S. Alasmari and collaborators from the Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia have published the Article: Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting Haloperidol Exposure in Healthy and Disease Populations, in the Journal: Pharmaceutics 2022, 14, 1795. of 25/07/2022
  • what: The model was initially developed and evaluated to predict the PK of haloperidol and its reduced metabolite in adult healthy population after intravenous and oral administration. The authors aim in this study to develop and evaluate whole-body parent . . .

     

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