Development and structure-activity relationships of tanshinones as selective

HIGHLIGHTS

  • who: Xu Deng from the State Key Laboratory of Phytochemistry and Plant Resources in West China have published the research work: Development and structure-activity relationships of tanshinones as selective, in the Journal: (JOURNAL)
  • what: 1 Chemistry Procedures for the synthesis of the compounds mentioned in this article and their characterization data, as well as the spectra copies, are described in Supplementary Information.
  • how: These results indicated that subtle changes in D-ring can dramatically affect the activity and selectivity against both human and mouse 11u03b2-HSD1 which is particularly true for human . . .

     

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