HIGHLIGHTS
- who: Johannes Delp from the (UNIVERSITY) have published the research: Development of a neurotoxicity assay that is tuned to detect mitochondrial toxicants, in the Journal: (JOURNAL)
- what: In this study, the Glc-Gal shift was explored as expansion of the test protocol. Hexoses can be metabolized to Pyr with the primary objective to enter Pyr as well as the excess NADH into the mitochondria to generate ATP via the mitochondrial respiratory_chain (MRC) activity. The authors evaluated the feasibility and usefulness of tuning the established NeuriTox assay to detect mitochondrial neurotoxicants more sensitively. The study shows . . .
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