Development of a ternary cyclodextrin-arginine-ciprofloxacin antimicrobial complex with enhanced stability

HIGHLIGHTS

• who: Marija Vukomanovic from the Institut University of have published the research work: Development of a ternary cyclodextrin-arginine-ciprofloxacin antimicrobial complex with enhanced stability, in the Journal: (JOURNAL) of 12/05/2022
• what: This approach has been applied to various antibiotics (u03b2-lactams microlides fluoroquinolones sulfonamides tetracyclines and aminoglycosides) and their minimal inhibitory concentrations (MICs) were reduced by factors from 2 to more than 10011. With this approach the goal was not simply increasing the solubility of the drug as usual.
• how: XPS data were analysed with PHI Multipak software.
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