Development of a vascularized human skin equivalent with hypodermis for photoaging studies

HIGHLIGHTS

• who: Martina M. Sanchez and collaborators from the Department of Bioengineering, University of California, Riverside, CA, USA have published the research work: Development of a Vascularized Human Skin Equivalent with Hypodermis for Photoaging Studies, in the Journal: Biomolecules 2022, 1828 of /2022/
• what: Building on the previously published protocol generating vascularized HSE (VHSE) , here the authors demonstrate inclusion of a hypodermis, which the authors term adipose and vascular human skin equivalent (AVHSE), and demonstrate suitability for UVA photoaging studies. Similar to prior models, the authors demonstrate AVHSEs appropriately model the skin epidermis with correct localization . . .
  

   

  

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