Development of an anti-car antibody response in siv-infected rhesus macaques treated with cd4-mbl car/cxcr5 t cells

HIGHLIGHTS

• who: Brianna C. Davey and colleagues from the National Institute of Allergy and United States University of California, Los Angeles have published the Article: Development of an anti-CAR antibody response in SIV-infected rhesus macaques treated with CD4-MBL CAR/CXCR5 T cells, in the Journal: (JOURNAL)
• what: The authors investigated whether an ADA response was produced in rhesus macaques treated with CD4-MBL CAR/ CXCR5-T_cells. The studies have utilized a bispecific CAR, which contains domains 1 and 2 (D1/D2) of CD4, targeting the CD4 binding_site on the viral envelope glycoprotein, gp120 . . .
  

   

  

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