Development of analgesics: a little help from mitogen and stress-activat- ed kinases 1 and 2

HIGHLIGHTS

• who: Istvan Nagy and collaborators from the College London, UK University of have published the research: Development of Analgesics: A Little Help from Mitogen and Stress-Activat- ed Kinases 1 and 2, in the Journal: (JOURNAL) of June/01,/2017
• what: Although MSK1/2-/- mice lack these enzymes globally, the importance of peripheral and spinal sensitisation in the development of prolonged pain suggests that the lack of MSK1/2 in primary sensory neurons and/or spinal dorsal horn neurons could be the major reason for the failure of inflammatory heat hypersensitivity to develop. Clerisy Publishers . . .
  

   

  

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