HIGHLIGHTS
- who: Xuan Yang and collaborators from the University of North Carolina at Chapel Hill, Chapel Hill, NC, USA have published the paper: Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells, in the Journal: Molecules 2023, 2950 of /2023/
- how: The authors conducted the probe titration studies in live HEK293 cells in the adherent (ADH) The authors conducted the probe titration studies livefound HEK293 in the adherent (ADH) was fused to the N-terminus of human PLK1 (NLuc-PLK1) gave a much stronger BRET format via energy transfer . . .
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