Development of clinical weekly-dose teriparatide acetate encapsulated dissolving microneedle patch for efficient treatment of osteoporosis

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  • who: Jeeho Sim and collaborators from the Department of Biotechnology, Yonsei University, Seoul, Korea have published the Article: Development of Clinical Weekly-Dose Teriparatide Acetate Encapsulated Dissolving Microneedle Patch for Efficient Treatment of Osteoporosis, in the Journal: Polymers 2022, 4027 of 26/09/2022
  • what: The authors evaluated the minimization of TA activity reduction during the drying process by adding trehalose to the formulation, which is a prerequisite for TADMNs. The authors showed that a double dose of TA-DMN exceeded the AUC of subcutaneous injection and that TA concentrations in rat plasma increased at . . .

     

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